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Inhibition of MEIS3 Generates Cetuximab Resistance through c-Met and Akt
INTRODUCTION: Although cetuximab has been widely used in the treatment of colon cancer, a large number of patients eventually develop drug resistance. Therefore, it is essential to clarify the mechanism of drug resistance. METHODS: In this study, we combined in silico analysis and a single guide RNA...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744183/ https://www.ncbi.nlm.nih.gov/pubmed/33376716 http://dx.doi.org/10.1155/2020/2046248 |