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Inhibition of MEIS3 Generates Cetuximab Resistance through c-Met and Akt

INTRODUCTION: Although cetuximab has been widely used in the treatment of colon cancer, a large number of patients eventually develop drug resistance. Therefore, it is essential to clarify the mechanism of drug resistance. METHODS: In this study, we combined in silico analysis and a single guide RNA...

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Detalles Bibliográficos
Autores principales: Cai, Ping, Xie, Yangyang, Dong, Mingjun, Zhu, Qiaoqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744183/
https://www.ncbi.nlm.nih.gov/pubmed/33376716
http://dx.doi.org/10.1155/2020/2046248