A Chemiluminescent Immunoassay for Osteocalcin in Human Serum and a Solution to the “Hook Effect”

A chemiluminescent immunoassay for human serum osteocalcin, or bone Gla protein, was established using a double-antibody sandwich model. Examination of the hook effect revealed that it was significantly reduced, and no hook effect was observed at an osteocalcin concentration of 4000 ng/mL. The estab...

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Detalles Bibliográficos
Autores principales: Han, Shuang, Xue, Yifeng, Zhang, Junlan, Huang, Jianrong, Liu, Xiuxia, Yang, Yankun, Bai, Zhonghu, Wang, Chunxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744234/
https://www.ncbi.nlm.nih.gov/pubmed/33376621
http://dx.doi.org/10.1155/2020/8891437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744234/
https://www.ncbi.nlm.nih.gov/pubmed/33376621
http://dx.doi.org/10.1155/2020/8891437

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