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A Chemiluminescent Immunoassay for Osteocalcin in Human Serum and a Solution to the “Hook Effect”
A chemiluminescent immunoassay for human serum osteocalcin, or bone Gla protein, was established using a double-antibody sandwich model. Examination of the hook effect revealed that it was significantly reduced, and no hook effect was observed at an osteocalcin concentration of 4000 ng/mL. The estab...
Autores principales: | Han, Shuang, Xue, Yifeng, Zhang, Junlan, Huang, Jianrong, Liu, Xiuxia, Yang, Yankun, Bai, Zhonghu, Wang, Chunxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744234/ https://www.ncbi.nlm.nih.gov/pubmed/33376621 http://dx.doi.org/10.1155/2020/8891437 |
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