Cargando…

A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding

Immunization with recombinant glycoprotein-based vaccines is a promising approach to induce protective immunity against viruses. However, the complex biosynthetic maturation requirements of these glycoproteins typically necessitate their production in mammalian cells to support their folding and pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Margolin, Emmanuel, Crispin, Max, Meyers, Ann, Chapman, Ros, Rybicki, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744475/
https://www.ncbi.nlm.nih.gov/pubmed/33343609
http://dx.doi.org/10.3389/fpls.2020.609207