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A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding
Immunization with recombinant glycoprotein-based vaccines is a promising approach to induce protective immunity against viruses. However, the complex biosynthetic maturation requirements of these glycoproteins typically necessitate their production in mammalian cells to support their folding and pos...
Autores principales: | Margolin, Emmanuel, Crispin, Max, Meyers, Ann, Chapman, Ros, Rybicki, Edward P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744475/ https://www.ncbi.nlm.nih.gov/pubmed/33343609 http://dx.doi.org/10.3389/fpls.2020.609207 |
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