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A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding

Immunization with recombinant glycoprotein-based vaccines is a promising approach to induce protective immunity against viruses. However, the complex biosynthetic maturation requirements of these glycoproteins typically necessitate their production in mammalian cells to support their folding and pos...

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Detalles Bibliográficos
Autores principales: Margolin, Emmanuel, Crispin, Max, Meyers, Ann, Chapman, Ros, Rybicki, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744475/
https://www.ncbi.nlm.nih.gov/pubmed/33343609
http://dx.doi.org/10.3389/fpls.2020.609207

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