Syk facilitates phagosome-lysosome fusion by regulating actin-remodeling in complement-mediated phagocytosis

Effective phagocytosis is crucial for host defense against pathogens. Macrophages entrap pathogens into a phagosome and subsequently acidic lysosomes fuse to the phagosome. Previous studies showed the pivotal role of actin-remodeling mediated by phosphoinositide-related signaling in phagosome format...

Descripción completa

Detalles Bibliográficos
Autores principales: Tabata, Hiroyuki, Morita, Hiroyuki, Kaji, Hiroaki, Tohyama, Kaoru, Tohyama, Yumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744523/
https://www.ncbi.nlm.nih.gov/pubmed/33328565
http://dx.doi.org/10.1038/s41598-020-79156-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744523/
https://www.ncbi.nlm.nih.gov/pubmed/33328565
http://dx.doi.org/10.1038/s41598-020-79156-7

Ejemplares similares