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Syk facilitates phagosome-lysosome fusion by regulating actin-remodeling in complement-mediated phagocytosis

Effective phagocytosis is crucial for host defense against pathogens. Macrophages entrap pathogens into a phagosome and subsequently acidic lysosomes fuse to the phagosome. Previous studies showed the pivotal role of actin-remodeling mediated by phosphoinositide-related signaling in phagosome format...

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Detalles Bibliográficos
Autores principales:	Tabata, Hiroyuki, Morita, Hiroyuki, Kaji, Hiroaki, Tohyama, Kaoru, Tohyama, Yumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744523/ https://www.ncbi.nlm.nih.gov/pubmed/33328565 http://dx.doi.org/10.1038/s41598-020-79156-7

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