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FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Asthma with severe exacerbation is the most common cause of hospitalization among young children. We aim to increase the understanding of this clinically important disease entity through a genome-wide association study. The discovery analysis comprises 2866 children experiencing severe asthma exacer...

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Detalles Bibliográficos
Autores principales: Ahluwalia, Tarunveer S., Eliasen, Anders U., Sevelsted, Astrid, Pedersen, Casper-Emil T., Stokholm, Jakob, Chawes, Bo, Bork-Jensen, Jette, Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Linneberg, Allan, Sharma, Amitabh, Weiss, Scott T., Evans, Michael D., Jackson, Daniel J., Morin, Andreanne, Krogfelt, Karen A., Schjørring, Susanne, Mortensen, Preben B., Hougaard, David M., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Mors, Ole, Nordentoft, Merete, Børglum, Anders D., Werge, Thomas, Agerbo, Esben, Gern, James E., Lemanske, Robert F., Ober, Carole, Pedersen, Anders G., Bisgaard, Hans, Bønnelykke, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744576/
https://www.ncbi.nlm.nih.gov/pubmed/33328473
http://dx.doi.org/10.1038/s41467-020-19814-6