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N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB

We previously identified the N-quinoline-benzenesulfonamide (NQBS) scaffold as a potent inhibitor of nuclear factor-κB (NF-κB) translocation. Now, we report the structure-activity relationship of compounds with the NQBS scaffold in models of diffuse large B-cell lymphoma (DLBCL). We identified CU-O4...

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Detalles Bibliográficos
Autores principales: Kalac, Matko, Mangone, Michael, Rinderspacher, Alison, Deng, Shi-Xian, Scotto, Luigi, Markson, Michael, Bansal, Mukesh, Califano, Andrea, Landry, Donald W., O'Connor, Owen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744703/
https://www.ncbi.nlm.nih.gov/pubmed/33354662
http://dx.doi.org/10.1016/j.isci.2020.101884