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N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB
We previously identified the N-quinoline-benzenesulfonamide (NQBS) scaffold as a potent inhibitor of nuclear factor-κB (NF-κB) translocation. Now, we report the structure-activity relationship of compounds with the NQBS scaffold in models of diffuse large B-cell lymphoma (DLBCL). We identified CU-O4...
Autores principales: | Kalac, Matko, Mangone, Michael, Rinderspacher, Alison, Deng, Shi-Xian, Scotto, Luigi, Markson, Michael, Bansal, Mukesh, Califano, Andrea, Landry, Donald W., O'Connor, Owen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744703/ https://www.ncbi.nlm.nih.gov/pubmed/33354662 http://dx.doi.org/10.1016/j.isci.2020.101884 |
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