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Determination of the physical state of a drug in amorphous solid dispersions using artificial neural networks and ATR-FTIR spectroscopy

The objective of the present study was to evaluate the use of artificial neural networks (ANNs) in the development of a new chemometric model that will be able to simultaneously distinguish and quantify the percentage of the crystalline and the neat amorphous drug located within the drug-rich amorph...

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Detalles Bibliográficos
Autores principales: Kapourani, Afroditi, Valkanioti, Vasiliki, Kontogiannopoulos, Konstantinos N., Barmpalexis, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744708/
https://www.ncbi.nlm.nih.gov/pubmed/33354666
http://dx.doi.org/10.1016/j.ijpx.2020.100064