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Negative volume changes of human G-quadruplexes at unfolding

G-quadruplexes are tetrahelical structures. They are important targets for anti-cancer drugs, since they are situated at crucial positions within the genome. We studied the volumetric properties of the unfolding of three G-quadruplexes in the presence of potassium ion. The unfolding volume changes w...

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Detalles Bibliográficos
Autores principales: Molnár, Orsolya Réka, Somkuti, Judit, Smeller, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744710/
https://www.ncbi.nlm.nih.gov/pubmed/33354631
http://dx.doi.org/10.1016/j.heliyon.2020.e05702