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Altered Insulin Receptor Substrate 1 Phosphorylation in Blood Neuron-Derived Extracellular Vesicles From Patients With Parkinson’s Disease

INTRODUCTION: Diabetes increases the risk of Parkinson’s disease (PD). The phosphorylation of type 1 insulin receptor substrate (IRS-1) determines the function of insulin signaling pathway. Extracellular vesicles (EVs) are emerging as biomarkers of human diseases. The present study investigated whet...

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Detalles Bibliográficos
Autores principales: Chou, Szu-Yi, Chan, Lung, Chung, Chen-Chih, Chiu, Jing-Yuan, Hsieh, Yi-Chen, Hong, Chien-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744811/
https://www.ncbi.nlm.nih.gov/pubmed/33344443
http://dx.doi.org/10.3389/fcell.2020.564641