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Intradermal delivery of receptor‐binding domain of SARS‐CoV‐2 spike protein with dissolvable microneedles to induce humoral and cellular responses in mice

The S1 subunit of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike protein contains an immunogenic receptor‐binding domain (RBD), which is a promising candidate for the development of a potential vaccine. This study demonstrated that intradermal delivery of an S‐RBD vaccine using a...

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Detalles Bibliográficos
Autores principales: Kuwentrai, Chaiyaporn, Yu, Jinming, Rong, Li, Zhang, Bao‐Zhong, Hu, Ye‐Fan, Gong, Hua‐Rui, Dou, Ying, Deng, Jian, Huang, Jian‐Dong, Xu, Chenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744900/
https://www.ncbi.nlm.nih.gov/pubmed/33349797
http://dx.doi.org/10.1002/btm2.10202