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Sources of Multidrug Resistance in Patients With Previous Isoniazid-Resistant Tuberculosis Identified Using Whole Genome Sequencing: A Longitudinal Cohort Study

BACKGROUND: Meta-analysis of patients with isoniazid-resistant tuberculosis (TB) given standard first-line anti-TB treatment indicated an increased risk of multidrug-resistant TB (MDR-TB) emerging (8%), compared to drug-sensitive TB (0.3%). Here we use whole genome sequencing (WGS) to investigate wh...

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Detalles Bibliográficos
Autores principales: Srinivasan, Vijay, Ha, Vu T N, Vinh, Dao N, Thai, Phan V K, Ha, Dang T M, Lan, Nguyen H, Hai, Hoang T, Walker, Timothy M, Thu, Do D A, Dunstan, Sarah J, Thwaites, Guy E, Ashton, Philip M, Caws, Maxine, Thuong, Nguyen T T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744982/
https://www.ncbi.nlm.nih.gov/pubmed/32166306
http://dx.doi.org/10.1093/cid/ciaa254