Pharmacokinetics, Safety, and Antiviral Effects of Multiple Doses of the Respiratory Syncytial Virus (RSV) Fusion Protein Inhibitor, JNJ-53718678, in Infants Hospitalized With RSV Infection: A Randomized Phase 1b Study

BACKGROUND: This phase 1b study evaluated the pharmacokinetics, safety, and antiviral effects of the respiratory syncytial virus (RSV)–specific fusion inhibitor JNJ-53718678 (JNJ-8678) in hospitalized RSV-infected patients aged > 1 to ≤24 months. METHODS: Patients categorized by age (cohort 1: ≥6...

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Detalles Bibliográficos
Autores principales: Martinón-Torres, Federico, Rusch, Sarah, Huntjens, Dymphy, Remmerie, Bart, Vingerhoets, Johan, McFadyen, Katie, Ferrero, Fernando, Baraldi, Eugenio, Rojo, Pablo, Epalza, Cristina, Stevens, Marita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744997/
https://www.ncbi.nlm.nih.gov/pubmed/32201897
http://dx.doi.org/10.1093/cid/ciaa283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744997/
https://www.ncbi.nlm.nih.gov/pubmed/32201897
http://dx.doi.org/10.1093/cid/ciaa283

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