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Co-delivery of 5-fluorodeoxyuridine and doxorubicin via gold nanoparticle equipped with affibody-DNA hybrid strands for targeted synergistic chemotherapy of HER2 overexpressing breast cancer

Combination chemotherapy is still of great importance as part of the standard clinical care for patients with HER2 positive breast cancer. As an attractive component, gold nanoparticles (AuNPs) have been extensively studied as biosafety nanomaterials, but they are rarely explored as drug nanocarrier...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Fanghua, Han, Mengnan, Wang, Xuming, Du, Jie, Zhang, Honglei, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745031/
https://www.ncbi.nlm.nih.gov/pubmed/33328545
http://dx.doi.org/10.1038/s41598-020-79125-0