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LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection

HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogeneous popul...

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Detalles Bibliográficos
Autores principales: Thakuri, Bal Krishna Chand, Zhang, Jinyu, Zhao, Juan, Nguyen, Lam N., Nguyen, Lam N. T., Khanal, Sushant, Cao, Dechao, Dang, Xindi, Schank, Madison, Wu, Xiao Y., Morrison, Zheng D., Gazzar, Mohamed El, Li, Zhengke, Jiang, Yong, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745042/
https://www.ncbi.nlm.nih.gov/pubmed/33328510
http://dx.doi.org/10.1038/s41598-020-78786-1