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LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection
HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogeneous popul...
Autores principales: | Thakuri, Bal Krishna Chand, Zhang, Jinyu, Zhao, Juan, Nguyen, Lam N., Nguyen, Lam N. T., Khanal, Sushant, Cao, Dechao, Dang, Xindi, Schank, Madison, Wu, Xiao Y., Morrison, Zheng D., Gazzar, Mohamed El, Li, Zhengke, Jiang, Yong, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745042/ https://www.ncbi.nlm.nih.gov/pubmed/33328510 http://dx.doi.org/10.1038/s41598-020-78786-1 |
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