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Selectively enhancing radiosensitivity of cancer cells via in situ enzyme-instructed peptide self-assembly

The radiotherapy modulators used in clinic have disadvantages of high toxicity and low selectivity. For the first time, we used the in situ enzyme-instructed self-assembly (EISA) of a peptide derivative (Nap-G(D)F(D)FpYSV) to selectively enhance the sensitivity of cancer cells with high alkaline pho...

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Detalles Bibliográficos
Autores principales: Gao, Yang, Gao, Jie, Mu, Ganen, Zhang, Yumin, Huang, Fan, Zhang, Wenxue, Ren, Chunhua, Yang, Cuihong, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745053/
https://www.ncbi.nlm.nih.gov/pubmed/33354508
http://dx.doi.org/10.1016/j.apsb.2020.07.022