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Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway

Multiple cancer immunotherapies including chimeric antigen receptor T cell and immune checkpoint inhibitors (ICIs) have been successfully developed to treat various cancers by motivating the adaptive anti-tumor immunity. Particularly, the checkpoint blockade approach has achieved great clinic succes...

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Detalles Bibliográficos
Autores principales: Ding, Chunyong, Song, Zilan, Shen, Ancheng, Chen, Tingting, Zhang, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745059/
https://www.ncbi.nlm.nih.gov/pubmed/33354501
http://dx.doi.org/10.1016/j.apsb.2020.03.001