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Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway
Multiple cancer immunotherapies including chimeric antigen receptor T cell and immune checkpoint inhibitors (ICIs) have been successfully developed to treat various cancers by motivating the adaptive anti-tumor immunity. Particularly, the checkpoint blockade approach has achieved great clinic succes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745059/ https://www.ncbi.nlm.nih.gov/pubmed/33354501 http://dx.doi.org/10.1016/j.apsb.2020.03.001 |