Targeting human MutT homolog 1 (MTH1) for cancer eradication: current progress and perspectives

Since accelerated metabolism produces much higher levels of reactive oxygen species (ROS) in cancer cells compared to ROS levels found in normal cells, human MutT homolog 1 (MTH1), which sanitizes oxidized nucleotide pools, was recently demonstrated to be crucial for the survival of cancer cells, bu...

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Detalles Bibliográficos
Autores principales: Yin, Yizhen, Chen, Fener
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745060/
https://www.ncbi.nlm.nih.gov/pubmed/33354500
http://dx.doi.org/10.1016/j.apsb.2020.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745060/
https://www.ncbi.nlm.nih.gov/pubmed/33354500
http://dx.doi.org/10.1016/j.apsb.2020.02.012

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