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Targeting human MutT homolog 1 (MTH1) for cancer eradication: current progress and perspectives
Since accelerated metabolism produces much higher levels of reactive oxygen species (ROS) in cancer cells compared to ROS levels found in normal cells, human MutT homolog 1 (MTH1), which sanitizes oxidized nucleotide pools, was recently demonstrated to be crucial for the survival of cancer cells, bu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745060/ https://www.ncbi.nlm.nih.gov/pubmed/33354500 http://dx.doi.org/10.1016/j.apsb.2020.02.012 |