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Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach†

Continuous flow chemistry has the potential to greatly improve efficiency in the synthesis of active pharmaceutical ingredients (APIs); however, the optimization of these processes can be complicated by a large number of variables affecting reaction success. In this work, a screening design of exper...

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Detalles Bibliográficos
Autores principales: Armstrong, Cameron T., Pritchard, Cailean Q., Cook, Daniel W., Ibrahim, Mariam, Desai, Bimbisar K., Whitham, Patrick J., Marquardt, Brian J., Chen, Yizheng, Zoueu, Jeremie T., Bortner, Michael J., Roper, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745113/
https://www.ncbi.nlm.nih.gov/pubmed/33456973
http://dx.doi.org/10.1039/c8re00252e