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Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach†
Continuous flow chemistry has the potential to greatly improve efficiency in the synthesis of active pharmaceutical ingredients (APIs); however, the optimization of these processes can be complicated by a large number of variables affecting reaction success. In this work, a screening design of exper...
Autores principales: | Armstrong, Cameron T., Pritchard, Cailean Q., Cook, Daniel W., Ibrahim, Mariam, Desai, Bimbisar K., Whitham, Patrick J., Marquardt, Brian J., Chen, Yizheng, Zoueu, Jeremie T., Bortner, Michael J., Roper, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745113/ https://www.ncbi.nlm.nih.gov/pubmed/33456973 http://dx.doi.org/10.1039/c8re00252e |
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