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A Versatile Isobaric Tag Enables Proteome Quantification in Data-Dependent and Data-Independent Acquisition Modes

[Image: see text] Quantifying proteins based on peptide-coupled reporter ions is a multiplexed quantitative strategy in proteomics that alleviates the problem of ratio distortion caused by peptide cofragmentation, as commonly observed in other reporter-ion-based approaches, such as TMT and iTRAQ. Da...

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Detalles Bibliográficos
Autores principales: Tian, Xiaobo, de Vries, Marcel P., Permentier, Hjalmar P., Bischoff, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745205/
https://www.ncbi.nlm.nih.gov/pubmed/33256395
http://dx.doi.org/10.1021/acs.analchem.0c03858