Baicalein Attenuates Neuroinflammation by Inhibiting NLRP3/Caspase-1/GSDMD Pathway in MPTP-Induced Mice Model of Parkinson’s Disease

BACKGROUND: Inflammasome-induced neuroinflammation is a major pathogenic mechanism underlying the degeneration of nigral dopaminergic neurons in Parkinson’s disease (PD). Baicalein is a flavonoid isolated from the traditional Chinese medicinal herbal Scutellaria baicalensis Georgi with known anti-in...

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Detalles Bibliográficos
Autores principales: Rui, Wenjuan, Li, Sheng, Xiao, Hong, Xiao, Ming, Shi, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745250/
https://www.ncbi.nlm.nih.gov/pubmed/32761175
http://dx.doi.org/10.1093/ijnp/pyaa060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745250/
https://www.ncbi.nlm.nih.gov/pubmed/32761175
http://dx.doi.org/10.1093/ijnp/pyaa060

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