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Improving CLIP-seq data analysis by incorporating transcript information

BACKGROUND: Current peak callers for identifying RNA-binding protein (RBP) binding sites from CLIP-seq data take into account genomic read profiles, but they ignore the underlying transcript information, that is information regarding splicing events. So far, there are no studies available that close...

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Detalles Bibliográficos
Autores principales: Uhl, Michael, Tran, Van Dinh, Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745353/
https://www.ncbi.nlm.nih.gov/pubmed/33334306
http://dx.doi.org/10.1186/s12864-020-07297-0