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Alpha-beta transition induced by C18-conjugation of polyalanine and its implication in aqueous solution behavior of poly(ethylene glycol)-polyalanine block copolymers

BACKGROUND: The aqueous solution behavior of thermosensitive PEG-PA block copolymers as well as secondary structure of PA is expected to significantly change through modification of the hydrophobic PA by long chain alkyl (C18) groups with different configurations. METHOD: Oleoyl and stearoyl (C18) g...

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Detalles Bibliográficos
Autores principales: Park, Min Hee, Park, Jinkyung, Lee, Hyun Jung, Jeong, Byeongmoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745361/
https://www.ncbi.nlm.nih.gov/pubmed/33334374
http://dx.doi.org/10.1186/s40824-020-00200-8