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Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na(+)/K(+)-ATPase β2: potential molecular entities to treat invasive brain cancer
BACKGROUND: Glioblastoma (GB) cells have the ability to migrate and infiltrate the normal parenchyma, leading to the formation of recurrent tumors often adjacent to the surgical extraction site. We recently showed that Phoneutria nigriventer spider venom (PnV) has anticancer effects mainly on the mi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745393/ https://www.ncbi.nlm.nih.gov/pubmed/33327966 http://dx.doi.org/10.1186/s12935-020-01643-8 |