Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na(+)/K(+)-ATPase β2: potential molecular entities to treat invasive brain cancer

BACKGROUND: Glioblastoma (GB) cells have the ability to migrate and infiltrate the normal parenchyma, leading to the formation of recurrent tumors often adjacent to the surgical extraction site. We recently showed that Phoneutria nigriventer spider venom (PnV) has anticancer effects mainly on the mi...

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Detalles Bibliográficos
Autores principales: Barreto, Natália, Caballero, Marcus, Bonfanti, Amanda Pires, de Mato, Felipe Cezar Pinheiro, Munhoz, Jaqueline, da Rocha‐e‐Silva, Thomaz A. A., Sutti, Rafael, Vitorino-Araujo, João Luiz, Verinaud, Liana, Rapôso, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745393/
https://www.ncbi.nlm.nih.gov/pubmed/33327966
http://dx.doi.org/10.1186/s12935-020-01643-8

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