Effects of Excipients on the Structure and Dynamics of Filgrastim Monitored by Thermal Unfolding Studies by CD and NMR Spectroscopy

[Image: see text] Product excipients are used to confer a number of desirable properties on the drug substance to maintain or improve stability and facilitate drug delivery. This is especially important for products where the active pharmaceutical ingredient (API) is a recombinant protein. In this s...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghasriani, Houman, Frahm, Grant E., Johnston, Michael J. W., Aubin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745408/
https://www.ncbi.nlm.nih.gov/pubmed/33344838
http://dx.doi.org/10.1021/acsomega.0c04692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745408/
https://www.ncbi.nlm.nih.gov/pubmed/33344838
http://dx.doi.org/10.1021/acsomega.0c04692

Ejemplares similares