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In Silico ADME, Metabolism Prediction and Hydrolysis Study of Melatonin Derivatives
Melatonin (MLT) is a well-known pineal hormone possessed with remarkable biological activities. However, its low oral bioavailability and high first-pass metabolism rate are important pharmacokinetics problems. Therefore, 5 MLT derivatives (1-5) were designed and synthesised in our group to solve th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745548/ https://www.ncbi.nlm.nih.gov/pubmed/33402831 http://dx.doi.org/10.1177/1178646920978245 |