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T and B Lymphocyte Deficiency in Rag1−/− Mice Reduces Retinal Ganglion Cell Loss in Experimental Glaucoma

PURPOSE: We previously demonstrated that passive transfer of lymphocytes from glaucomatous mice induces retinal ganglion cell (RGC) damage in recipient animals, suggesting a role for immune responses in the multifactorial pathophysiology of glaucoma. Here we evaluate whether absence of an adaptive i...

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Detalles Bibliográficos
Autores principales: Gramlich, Oliver W., Godwin, Cheyanne R., Heuss, Neal D., Gregerson, Dale S., Kuehn, Markus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745626/
https://www.ncbi.nlm.nih.gov/pubmed/33320171
http://dx.doi.org/10.1167/iovs.61.14.18