Candidate Genetic Modifiers for RPGR Retinal Degeneration

PURPOSE: To define genetic variants associated with variable severity of X-linked progressive retinal atrophy 1 (XLPRA1) caused by a five-nucleotide deletion in canine RPGR exon ORF15. METHODS: A genome-wide association study (GWAS) was performed in XLPRA1 phenotype informative pedigree. Whole genom...

Descripción completa

Detalles Bibliográficos
Autores principales: Appelbaum, Tatyana, Murgiano, Leonardo, Becker, Doreen, Santana, Evelyn, Aguirre, Gustavo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745631/
https://www.ncbi.nlm.nih.gov/pubmed/33326016
http://dx.doi.org/10.1167/iovs.61.14.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745631/
https://www.ncbi.nlm.nih.gov/pubmed/33326016
http://dx.doi.org/10.1167/iovs.61.14.20

Ejemplares similares