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Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations

BACKGROUND: Previous studies have shown the value in studying lineage tracing in slices of human tumors. However, a tumor is not a two-dimensional structure and to better understand how a tumor, and its corresponding metastasis grow, a three-dimensional (3-D) view is necessary. RESULTS: Using somati...

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Detalles Bibliográficos
Autores principales: Refinetti, Paulo, Morgenthaler, Stephan, Thilly, William G., Arstad, Christian, Ekstrøm, Per O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745703/
https://www.ncbi.nlm.nih.gov/pubmed/33344219
http://dx.doi.org/10.3389/fonc.2020.523860