Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors

Epigenetic mechanisms are involved in epilepsy and chronic pain development. About that, we studied the effects of the natural histone deacetylase (HDAC) inhibitor sodium butyrate (BUT) in comparison with valproic acid (VPA) in a validated genetic model of generalized absence epilepsy and epileptoge...

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Detalles Bibliográficos
Autores principales: De Caro, Carmen, Di Cesare Mannelli, Lorenzo, Branca, Jacopo Junio Valerio, Micheli, Laura, Citraro, Rita, Russo, Emilio, De Sarro, Giovambattista, Ghelardini, Carla, Calignano, Antonio, Russo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745735/
https://www.ncbi.nlm.nih.gov/pubmed/33343343
http://dx.doi.org/10.3389/fphar.2020.549191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745735/
https://www.ncbi.nlm.nih.gov/pubmed/33343343
http://dx.doi.org/10.3389/fphar.2020.549191

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