Cargando…

Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors

Epigenetic mechanisms are involved in epilepsy and chronic pain development. About that, we studied the effects of the natural histone deacetylase (HDAC) inhibitor sodium butyrate (BUT) in comparison with valproic acid (VPA) in a validated genetic model of generalized absence epilepsy and epileptoge...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Caro, Carmen, Di Cesare Mannelli, Lorenzo, Branca, Jacopo Junio Valerio, Micheli, Laura, Citraro, Rita, Russo, Emilio, De Sarro, Giovambattista, Ghelardini, Carla, Calignano, Antonio, Russo, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745735/ https://www.ncbi.nlm.nih.gov/pubmed/33343343 http://dx.doi.org/10.3389/fphar.2020.549191

Ejemplares similares

Investigation of ECG Changes in Absence Epilepsy on WAG/Rij Rats
por: Es'haghi, Fatemeh, et al.
Publicado: (2015)

PT607. Effect of Neural Stem Cell Transplantation on Absence Seizures in Genetic Absence Epileptic WAG/Rij Rats
por: Utkan, Tijen, et al.
Publicado: (2016)

PT606. Effects of Chronic Ethosuximide Treatment on Cardiovascular Changes in Genetic Absence Epileptic WAG/Rij Rats
por: Şahin, Tuğçe Demirtaş, et al.
Publicado: (2016)

The Effect of Ciprofloxacin Injection on Genetically Absence Prone (Wag/Rij) Rat's Electroencephalogram Characteristics
por: Moghimi, Ali, et al.
Publicado: (2013)

Lamotrigine effects sensorimotor gating in WAG/Rij rats
por: Celikyurt, Ipek Komsuoglu, et al.
Publicado: (2012)

Age-dependent decline in learning and memory performances of WAG/Rij rat model of absence epilepsy
por: Karson, Ayşe, et al.
Publicado: (2012)

Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats
por: Brunner, Brigitta, et al.
Publicado: (2021)

An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities
por: Wemhöner, Konstantin, et al.
Publicado: (2015)

Erratum: Age-dependent decline in learning and memory performances of WAG/Rij rat model of absence epilepsy
por: Karson, Ayşe, et al.
Publicado: (2015)

Reduction of Hippocampal High-Frequency Activity in Wag/Rij Rats with a Genetic Predisposition to Absence Epilepsy
por: Sitnikova, Evgenia, et al.
Publicado: (2022)

Antidepressant and Anxiolytic Effects of L-Methionine in the WAG/Rij Rat Model of Depression Comorbid with Absence Epilepsy
por: Sarkisova, Karine Yu., et al.
Publicado: (2023)

Effects of Postnatal Caffeine Exposure on Absence Epilepsy and Comorbid Depression: Results of a Study in WAG/Rij Rats
por: Ilbay, Gul, et al.
Publicado: (2022)

Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats?
por: Moyanova, Slavianka, et al.
Publicado: (2018)

Intestinal inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a mouse model of epilepsy
por: De Caro, Carmen, et al.
Publicado: (2019)

Sleep Disturbances in Rats With Genetic Pre-disposition to Spike-Wave Epilepsy (WAG/Rij)
por: Sitnikova, Evgenia
Publicado: (2021)

Spike-Wave Seizures, NREM Sleep and Micro-Arousals in WAG/Rij Rats with Genetic Predisposition to Absence Epilepsy: Developmental Aspects
por: Zhuravlev, Maxim, et al.
Publicado: (2022)

440 Modulating decreases in Superior Colliculus activity through optogenetic activation attenuates seizures in the WAG/Rij genetic model of Absence Epilepsy
por: Palmer, Devin D., et al.
Publicado: (2022)

The Role of NMDA Receptors in the Effect of Purinergic P2X7 Receptor on Spontaneous Seizure Activity in WAG/Rij Rats With Genetic Absence Epilepsy
por: Doǧan, Elif, et al.
Publicado: (2020)

Neonatal Tactile Stimulation Downregulates Dendritic Spines in Layer V Pyramidal Neurons of the WAG/Rij Rat Somatosensory Cortex
por: Ilbay, Gul, et al.
Publicado: (2022)

Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats
por: Sarkisova, Karine Yu., et al.
Publicado: (2023)

Effects of 5-Ion Beam Irradiation and Hindlimb Unloading on Metabolic Pathways in Plasma and Brain of Behaviorally Tested WAG/Rij Rats
por: Raber, Jacob, et al.
Publicado: (2021)

Dose-Dependent Beneficial Effect of Ketone Supplement-Evoked Ketosis on Anxiety Level in Female WAG/Rij Rats: Sometimes Less Is More
por: Rauch, Enikő, et al.
Publicado: (2023)

Phaseolus vulgaris L. Extract: Alpha-Amylase Inhibition against Metabolic Syndrome in Mice
por: Micheli, Laura, et al.
Publicado: (2019)

Effects of gestational and lactational exposure to low dose mercury chloride (HgCl(2)) on behaviour, learning and hearing thresholds in WAG/Rij rats
por: Sahin, Deniz, et al.
Publicado: (2016)

Audiogenic epileptic DBA/2 mice strain as a model of genetic reflex seizures and SUDEP
por: Bosco, Francesca, et al.
Publicado: (2023)

Analgesic and Anti-Inflammatory Effects of Perampanel in Acute and Chronic Pain Models in Mice: Interaction With the Cannabinergic System
por: De Caro, Carmen, et al.
Publicado: (2021)

Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders
por: Tallarico, Martina, et al.
Publicado: (2023)

Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side Effect
por: Branca, Jacopo Junio Valerio, et al.
Publicado: (2021)

Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice
por: D'Agostino, Giuseppe, et al.
Publicado: (2015)

Effect of NIR laser therapy by MLS-MiS source against neuropathic pain in rats: in vivo and ex vivo analysis
por: Micheli, Laura, et al.
Publicado: (2019)

Effects of the Combination of β-Hydroxy-β-Methyl Butyrate and R(+) Lipoic Acid in a Cellular Model of Sarcopenia
por: Mannelli, Lorenzo Di Cesare, et al.
Publicado: (2020)

Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism
por: Di Cesare Mannelli, L., et al.
Publicado: (2013)

Cannabidiol Protects Dopaminergic Neuronal Cells from Cadmium
por: Branca, Jacopo Junio Valerio, et al.
Publicado: (2019)

Pharmacovigilance in Calabria (Italy): Local experiences resonate international relevance
por: Russo, Emilio, et al.
Publicado: (2013)

The tail wagging the dog
por: Kelly, Patrick J.
Publicado: (2010)

Worth of a Wag
Publicado: (1879)

Worth of a Wag
Publicado: (1873)

Neural Modulation of the Primary Auditory Cortex by Intracortical Microstimulation with a Bio-Inspired Electronic System
por: Bianco, Maria Giovanna, et al.
Publicado: (2020)

An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists
por: Citraro, Rita, et al.
Publicado: (2023)

Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures
por: Mumoli, Laura, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h5haog17o2rnmqiooqllfuh5pn