Shrinkage improves estimation of microbial associations under different normalization methods

Estimation of statistical associations in microbial genomic survey count data is fundamental to microbiome research. Experimental limitations, including count compositionality, low sample sizes and technical variability, obstruct standard application of association measures and require data normaliz...

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Detalles Bibliográficos
Autores principales: Badri, Michelle, Kurtz, Zachary D, Bonneau, Richard, Müller, Christian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745771/
https://www.ncbi.nlm.nih.gov/pubmed/33575644
http://dx.doi.org/10.1093/nargab/lqaa100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745771/
https://www.ncbi.nlm.nih.gov/pubmed/33575644
http://dx.doi.org/10.1093/nargab/lqaa100

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