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Network preservation reveals shared and unique biological processes associated with chronic alcohol abuse in NAc and PFC

Chronic alcohol abuse has been linked to the disruption of executive function and allostatic conditioning of reward response dysregulation in the mesocorticolimbic pathway (MCL). Here, we analyzed genome-wide mRNA and miRNA expression from matched cases with alcohol dependence (AD) and controls (n =...

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Detalles Bibliográficos
Autores principales: Vornholt, Eric, Drake, John, Mamdani, Mohammed, McMichael, Gowon, Taylor, Zachary N., Bacanu, Silviu-Alin, Miles, Michael F., Vladimirov, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745987/
https://www.ncbi.nlm.nih.gov/pubmed/33332381
http://dx.doi.org/10.1371/journal.pone.0243857