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PRD-2 directly regulates casein kinase I and counteracts nonsense-mediated decay in the Neurospora circadian clock

Circadian clocks in fungi and animals are driven by a functionally conserved transcription–translation feedback loop. In Neurospora crassa, negative feedback is executed by a complex of Frequency (FRQ), FRQ-interacting RNA helicase (FRH), and casein kinase I (CKI), which inhibits the activity of the...

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Detalles Bibliográficos
Autores principales: Kelliher, Christina M, Lambreghts, Randy, Xiang, Qijun, Baker, Christopher L, Loros, Jennifer J, Dunlap, Jay C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746235/
https://www.ncbi.nlm.nih.gov/pubmed/33295874
http://dx.doi.org/10.7554/eLife.64007