Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles

The novel coronavirus SARS-CoV-2 is the causative agent of Coronavirus Disease 2019 (COVID-19), a global healthcare and economic catastrophe. Understanding of the host immune response to SARS-CoV-2 is still in its infancy. A 382-nt deletion strain lacking ORF8 (Δ382 herein) was isolated in Singapore...

Descripción completa

Detalles Bibliográficos
Autores principales: Gamage, Akshamal M., Tan, Kai Sen, Chan, Wharton O. Y., Liu, Jing, Tan, Chee Wah, Ong, Yew Kwang, Thong, Mark, Andiappan, Anand K., Anderson, Danielle E., Wang, De Yun, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746279/
https://www.ncbi.nlm.nih.gov/pubmed/33284849
http://dx.doi.org/10.1371/journal.ppat.1009130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746279/
https://www.ncbi.nlm.nih.gov/pubmed/33284849
http://dx.doi.org/10.1371/journal.ppat.1009130

Ejemplares similares