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3D genome evolution and reorganization in the Drosophila melanogaster species group

Topologically associating domains, or TADs, are functional units that organize chromosomes into 3D structures of interacting chromatin. TADs play an important role in regulating gene expression by constraining enhancer-promoter contacts and there is evidence that deletion of TAD boundaries leads to...

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Detalles Bibliográficos
Autores principales: Torosin, Nicole S., Anand, Aparna, Golla, Tirupathi Rao, Cao, Weihuan, Ellison, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746282/
https://www.ncbi.nlm.nih.gov/pubmed/33284803
http://dx.doi.org/10.1371/journal.pgen.1009229