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In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species

The coronavirus disease COVID-19 constitutes the most severe pandemic of the last decades having caused more than 1 million deaths worldwide. The SARS-CoV-2 virus recognizes the angiotensin converting enzyme 2 (ACE2) on the surface of human cells through its spike protein. It has been reported that...

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Detalles Bibliográficos
Autores principales: Delgado Blanco, Javier, Hernandez-Alias, Xavier, Cianferoni, Damiano, Serrano, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746295/
https://www.ncbi.nlm.nih.gov/pubmed/33284795
http://dx.doi.org/10.1371/journal.pcbi.1008450