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Cell differentiation and aging accompanied by depletion of the ACE2 protein

ACE2 was observed as the cell surface receptor of the SARS-CoV-2 virus. Interestingly, we also found ACE2 positivity inside the cell nucleus. The ACE2 levels changed during cell differentiation and aging and varied in distinct cell types. We observed ACE2 depletion in the aortas of aging female mice...

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Detalles Bibliográficos
Autores principales: Bártová, Eva, Legartová, Soňa, Krejčí, Jana, Arcidiacono, Orazio Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746349/
https://www.ncbi.nlm.nih.gov/pubmed/33203793
http://dx.doi.org/10.18632/aging.202221