The therapeutic value of XL388 in human glioma cells

XL388 is a highly efficient and orally-available ATP-competitive PI3K-mTOR dual inhibitor. Its activity against glioma cells was studied here. In established and primary human glioma cells, XL388 potently inhibited cell survival and proliferation as well as cell migration, invasion and cell cycle pr...

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Detalles Bibliográficos
Autores principales: Zhong, Shan, Xue, Jun, Cao, Jiao-Jiao, Sun, Bomin, Sun, Qing-Fang, Bian, Liu-Guan, Hu, Liang-Yun, Pan, Si-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746352/
https://www.ncbi.nlm.nih.gov/pubmed/33159013
http://dx.doi.org/10.18632/aging.103791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746352/
https://www.ncbi.nlm.nih.gov/pubmed/33159013
http://dx.doi.org/10.18632/aging.103791

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