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The therapeutic value of XL388 in human glioma cells
XL388 is a highly efficient and orally-available ATP-competitive PI3K-mTOR dual inhibitor. Its activity against glioma cells was studied here. In established and primary human glioma cells, XL388 potently inhibited cell survival and proliferation as well as cell migration, invasion and cell cycle pr...
Autores principales: | Zhong, Shan, Xue, Jun, Cao, Jiao-Jiao, Sun, Bomin, Sun, Qing-Fang, Bian, Liu-Guan, Hu, Liang-Yun, Pan, Si-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746352/ https://www.ncbi.nlm.nih.gov/pubmed/33159013 http://dx.doi.org/10.18632/aging.103791 |
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