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Cationic solid lipid nanoparticles loaded by integrin β1 plasmid DNA attenuates IL-1β-induced apoptosis of chondrocyte

Aging-related inflammation is tightly linked with the development of osteoarthritis (OA). As the pro-inflammatory cytokine, IL-1β has been associated with physical dysfunction and frailty. It is still elusive whether and how IL-1β blockade improves the outcome of OA. Here we develop a cationic solid...

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Detalles Bibliográficos
Autores principales: Zhao, Yuejiang, Chen, Hanwen, Wang, Lu, Guo, Zhiyuan, Liu, Shijie, Luo, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746374/
https://www.ncbi.nlm.nih.gov/pubmed/33289706
http://dx.doi.org/10.18632/aging.103656