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Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation
Abnormal DNA methylation is a major early contributor to colon cancer (COAD) development. We conducted a cohort-based systematic investigation of genome-wide DNA methylation using 299 COAD and 38 normal tissue samples from TCGA. Through conditional screening and machine learning with a training coho...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746390/ https://www.ncbi.nlm.nih.gov/pubmed/33202377 http://dx.doi.org/10.18632/aging.103874 |