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Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation

Abnormal DNA methylation is a major early contributor to colon cancer (COAD) development. We conducted a cohort-based systematic investigation of genome-wide DNA methylation using 299 COAD and 38 normal tissue samples from TCGA. Through conditional screening and machine learning with a training coho...

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Detalles Bibliográficos
Autores principales: Wang, Yilin, Zhang, Ming, Hu, Xiaoyun, Qin, Wenyan, Wu, Huizhe, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746390/
https://www.ncbi.nlm.nih.gov/pubmed/33202377
http://dx.doi.org/10.18632/aging.103874