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Proposing a minimal set of metrics and methods to predict probabilities of amyloidosis disease and onset age in individuals

Many amyloid-driven pathologies have both genetic and stochastic components where assessing risk of disease development requires a multifactorial assessment where many of the variables are poorly understood. Risk of transthyretin-mediated amyloidosis is enhanced by age and mutation of the transthyre...

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Detalles Bibliográficos
Autores principales: Criddle, Richard S., Lin, Hsien-Jung L., James, Isabella, Park, Ji Sun, Hansen, Lee D., Price, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746394/
https://www.ncbi.nlm.nih.gov/pubmed/33203794
http://dx.doi.org/10.18632/aging.202208